High Throughput Screening Enables Scientists to Develop New Drugs

Accomplished in the fields of biochemistry and molecular biology, Jef Boeke, PhD, is the founder of the Baltimore-based High Throughput Biology Center, also referred to by the acronym HiT. The research division is overseen by Dr. Jef Boeke in collaboration with Dr. Min Li.

Part of the Johns Hopkins Institute for Basic Biomedical Sciences, also referred to as the IBBS, the High Throughput Biology Center has been set up to study the various disciplines related to biologic research and study. These areas include biology, computer science, math, chemistry, physics, and engineering, all of which are used in high-throughput methods or screening.

High-throughput screening, or HTS, is an experimental process that is conducted with the use of software, robotics, and related devices for genetic or pharmacological testing. HTS enables scientists to identify and record genes, antibodies, or biological or chemical compounds.

By using the screening method, scientists can better understand biochemical reactions or speed up the creation of new hypotheses. This type of study can assist researchers in developing models for new drugs as well.

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